Ladies hair medical salon

Those who are worried about gray hair

Those who are worried about gray hair

There is still no clear treatment for gray hair. Therefore, the majority of people dye their gray hair to repair it while damaging it. We wondered about this method of treatment and came up with the best solution for gray hair.
We clarify the causes and mechanisms of gray hair from a doctor's perspective, and propose specific measures and effective prevention and treatment methods based on medical evidence and our hospital's track record. If you are worried about gray hair, please read this.

1.Mechanism of hair color

When the mechanism of black hair is normal, melanocyte stem cells differentiate into melanocytes (pigment cells). Due to this action, melanocytes produce melanin pigment, which is deposited on keratinocytes, which are the main constituent of hair, giving hair its color.

Those who are worried about gray hair

2.causes of gray hair

Aging
Most of the causes of gray hair are aging, and the timing of gray hair can be said to have a large influence on genetics.
stress
Next to aging, lifestyle factors such as stress, poor nutrition, and lack of sleep are the leading causes of gray hair.

3.Gray hair due to aging

Gray hair associated with aging is said to be irreversible in most cases. Gray hair associated with aging is a phenomenon in which melanocyte stem cells gradually become depleted. This is caused by oxidative stress.
Below is a hair follicle bulb taken from the scalp of the same 64-year-old woman. A is a normal hair follicle that produces a lot of melanin, and b is a hair follicle that has only a small number of gray hair follicle melanocytes and almost no melanin production. The difference between the two is obvious.

Gray hair due to aging
Tobin DJ. Curr Probl Dermatol 2015;47:128-138

[Treatment for age-related gray hair]

The following things have been confirmed in gray hair follicles, so it may be possible to maintain melanin production even after hair turns gray.

・Melanocytes remain in the “outer root sheath”
・There is a reaction in which melanocytes are trying to produce melanin.
・Even though there is a lot of melanin, there is a phenomenon in which the hair matrix cells do not receive it.

Melanocytes do not completely disappear in hair that has turned white due to gray hair, so it is important to delay and prevent hair root aging in order to make use of the melanocytes that survive in the outer hair root sheath. is.

As a specific measure...

①Create the scalp environment and promote blood circulation with medical head spa
② Activate cells by directly supplementing the scalp with growth factors, exosomes, etc. using mesotherapy etc.
Gray hair due to aging

4.due to stress
Gray hair mechanism

Some of the melanocyte stem cells normally present in the “bulge” differentiate into melanocytes and produce melanin pigment. When stress is applied, sympathetic nerves are activated, noradrenaline increases, and all melanocyte stem cells in the bulge differentiate into melanocytes. This causes the melanocyte stem cells to become depleted, causing the hair to turn white as there are no more melanocytes to color the hair that will grow back in the next hair cycle. This is the mechanism by which hair turns gray due to stress. (Figure1-b)

Below is a hair follicle bulb taken from the scalp of the same 64-year-old woman. A is a normal hair follicle that produces a lot of melanin, and b is a hair follicle that has only a small number of gray hair follicle melanocytes and almost no melanin production. The difference between the two is obvious.

Mechanism of gray hair caused by stress
Clark SA, Deppmann CD. Nature 2020;577:623-624

[Stress gray hair is reversible]

The experimental results below show that stress gray hair is reversible. In other words, it is thought that melanocyte stem cells have not completely disappeared. From this, we will propose measures that activate melanocyte stem cells and are effective in improving stress gray hair. *The conclusion is the same as gray hair due to aging.

①Create the scalp environment and promote blood circulation with medical head spa
② Activate melanocytes by directly supplementing the scalp with growth factors and exosomes using mesotherapy
- Experimental results showing the appearance and improvement of gray hair in conjunction with increases and decreases in stress -
Mechanism of gray hair caused by stress
Rosenberg AM, et al. Elife 2021;10:e67437

Treatment Cases

At our hospital, we use hair care based on evidence,
AGA treatment and medical head spa
We offer the latest combination of treatments.

Age: 32 years old / Problem: Gray hair / Treatment period: 10 months

Before treatment
Before treatment
After treatment
After treatment
[Scalp case photo]
Before treatment
Before treatment
After treatment
After treatment
[Skin case photos]
Before treatment
Before treatment
After treatment
After treatment
*When you take care of your scalp, you will notice changes in your skin.
● Treatment plan Hair quality improvement injection plan
● Treatment cost 40,500 yen (44,550 yen including tax)/month
● Medical head spa None
● Thinning hair areas Mixed hairline and crown

Possible side effects: scalp itching, inflammation, etc.

[Scalp diagnosis data]
[Scalp diagnosis data]

Age: 31 years old / Problem: Curly hair / Treatment period: 1 year

Before treatment
Before treatment
After treatment
After treatment
[Scalp case photo]
Before treatment
Before treatment
After treatment
After treatment
[Skin case photos]
Before treatment
Before treatment
After treatment
After treatment
*When you take care of your scalp, you will notice changes in your skin.
● Treatment plan Hair quality improvement injection plan
● Treatment cost 8,000 yen (8,800 yen including tax)/month
● Medical head spa 4 time/month
● Thinning hair areas Mixed hairline and crown

Possible side effects: swelling, palpitations, tachycardia, decreased libido, liver dysfunction, etc.

[Scalp diagnosis data]
[Scalp diagnosis data]

Age: 31 years old / Concerns: Dandruff and itching / Treatment period: 1 year

Before treatment
Before treatment
After treatment
After treatment
[Scalp case photo]
Before treatment
Before treatment
After treatment
After treatment
[Skin case photos]
Before treatment
Before treatment
After treatment
After treatment
*When you take care of your scalp, you will notice changes in your skin.
● Treatment plan Hair quality improvement injection plan
● Treatment cost 8,000 yen (8,800 yen including tax)/month
● Medical head spa 4 time/month
● Thinning hair areas Mixed hairline and crown

Possible side effects: swelling, palpitations, tachycardia, decreased libido, liver dysfunction, etc.

[Scalp diagnosis data]
[Scalp diagnosis data]

Age: 31 years old / Concern: Hair type / Treatment period: 1 year

Before treatment
Before treatment
After treatment
After treatment
[Scalp case photo]
Before treatment
Before treatment
After treatment
After treatment
[Skin case photos]
Before treatment
Before treatment
After treatment
After treatment
*When you take care of your scalp, you will notice changes in your skin.
● Treatment plan Hair quality improvement injection plan
● Treatment cost 8,000 yen (8,800 yen including tax)/month
● Medical head spa 4 time/month
● Thinning hair areas Mixed hairline and crown

Possible side effects: swelling, palpitations, tachycardia, decreased libido, liver dysfunction, etc.

[Scalp diagnosis data]
[Scalp diagnosis data]

Age: 58 years old / Problem: Thinning hair / Treatment period: 1 year

Before treatment
Before treatment
After treatment
After treatment
[Scalp case photo]
Before treatment
Before treatment
After treatment
After treatment
[Skin case photos]
Before treatment
Before treatment
After treatment
After treatment
● Treatment plan Hair growth full support plan
● Treatment cost 122,000 yen (134,200 yen including tax)/month
● Medical head spa 1 time/month
● Thinning hair areas Mixed hairline and crown

Possible side effects: hirsutism, swelling, palpitations, dizziness, scalp itching/inflammation, etc.

[Scalp diagnosis data]
[Scalp diagnosis data]
*The case data is from those who have cooperated with the monitor in the past.

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